FR-901464

FR-901464
  • CAS No.:146478-72-0
  • Grade:90%
  • Formula:C27H41NO8
  • M.W.:507.62
  • Solvent:Soluble in methanol

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

It is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. Source summary: FR-901464 is a spliceosome inhibitor used as an ADC payload, inducing apoptosis in cancer cells by modulating RNA splicing.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Infection | Antibiotic

Product Information

  • Catalog No.: B2695-292577
  • CAS No.: 146478-72-0
  • Molecular Formula: C27H41NO8
  • Molecular Weight: 507.62
  • Purity: 90%
  • Storage: Store at -20°C
  • Solubility: Soluble in methanol

Source

Original product source


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