FR-901464

Overview

It is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. Source summary: FR-901464 is a spliceosome inhibitor used as an ADC payload, inducing apoptosis in cancer cells by modulating RNA splicing.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Infection | Antibiotic

Product Information

• Catalog No.: B2695-292577
• CAS No.: 146478-72-0
• Molecular Formula: C27H41NO8
• Molecular Weight: 507.62
• Purity: 90%
• Storage: Store at -20°C
• Solubility: Soluble in methanol

Source

Original product source