Acid-PEG5-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. Please contact us for GMP-grade inquiries.
PEGylation of Protein, Peptide & Oligo > Amine Reactive > PEG Acid | Antibody Drug Conjugates > Amine Reactive > PEG Acid | Drug Delivery, Surface Modification > Amine Reactive > PEG Acid | Products > PEG Linkers > PEG Acid | Products > PEG Linkers > PEG Acid > Acid-PEG-t-butyl ester
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