Mal-PEG6-PFP

Overview

Mal-PEG6-PFP is a PEG linker with maleimide and PFP moieties. Maleimides are thiol reactive between pH 6.5 and 7.5, forming thiolester bonds. The PFP is amine reactive and forms stable amide bonds. PFP was also found to be less susceptible toward hydrolysis than other amine reactive groups. The hydrophilic PEG linker increases the water solubility of a compound in aqueous environments. Increasing the number of units in the PEG chain ehnahces their solubility properties. Please contact us for GMP-grade inquiries.

Application

PEGylation of Protein, Peptide & Oligo > Thiol Reactive > Maleimide Linkers | Antibody Drug Conjugates > Thiol Reactive > Maleimide Linkers | Drug Delivery, Surface Modification > Thiol Reactive > Maleimide Linkers | Products > PEG Linkers > Maleimide Linkers | Products > PEG Linkers > Maleimide Linkers > Mal-PEG-PFP ester

Product Information

• Catalog No.: BP-21008
• CAS No.: 1599486-33-5
• Molecular Formula: C25H30F5NO10
• Molecular Weight: 599.5
• Purity: 98%
• Storage: -20°C
• Solubility: DMSO, DCM, DMF
• Availability: In Stock

Source

Original product source