Aminooxy-PEG3-acid HCl salt is a PEG linker containing an aminooxy group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Please contact us for GMP-grade inquiries. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
PEGylation of Protein, Peptide & Oligo > Amine Reactive > PEG Acid | Antibody Drug Conjugates > Amine Reactive > PEG Acid | PEGylation of Protein, Peptide & Oligo > Carbonyl Reactive > Aminooxy PEG | Antibody Drug Conjugates > Carbonyl Reactive > Aminooxy PEG | Drug Delivery, Surface Modification > Amine Reactive > PEG Acid | Drug Delivery, Surface Modification > Carbonyl Reactive > Aminooxy PEG | Products > PEG Linkers > Aminooxy PEG | Products > PEG Linkers > Aminooxy PEG > Aminooxy-PEG-acid | Products > PEG Linkers > PEG Acid > Aminoxy-PEG-acid
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