4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid

Overview

4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Please contact us for GMP-grade inquiries.

Application

PEGylation of Protein, Peptide & Oligo > Thiol Reactive > Maleimide Linkers | Antibody Drug Conjugates > Thiol Reactive > Maleimide Linkers | Drug Delivery, Surface Modification > Thiol Reactive > Maleimide Linkers | Products > PROTAC, Molecular glue > Aliphatic Linkers | Products > PEG Linkers > Maleimide Linkers > Mal-Alkyl-acid | Products > PROTAC, Molecular glue > Aliphatic Linkers > Mal-aliphatic-acid

Product Information

• Catalog No.: BP-21999
• CAS No.: 57078-98-5
• Molecular Formula: C8H9NO4
• Molecular Weight: 183.2
• Purity: 96%
• Storage: -20°C
• Availability: In Stock

Source

Original product source