Desthiobiotin-PEG3-NHS ester

CAS No.：2411681-92-8
Grade：95%
Formula：C23H38N4O9
M.W.：514.6
Solvent：Water, DMSO, DCM, DMF

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. Please contact us for GMP-grade inquiries.

Application

Products > PEG Linkers > Biotin PEG | Products > PEG Linkers > Biotin PEG > Biotin-PEG-NHS | Products > Biotinylation reagents > Amine Reactive > Biotin-NHS ester

Product Information

Catalog No.: BP-24457
CAS No.: 2411681-92-8
Molecular Formula: C23H38N4O9
Molecular Weight: 514.6
Purity: 95%
Storage: -20°C
Solubility: Water, DMSO, DCM, DMF
Availability: In Stock

Source

Original product source

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