BP Lipid 142

CAS No.：2244715-87-3
Grade：98%
Formula：C45H89NO5
M.W.：724.2
Solvent：Ethanol, DMSO, DMF

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

BP Lipid 142 is an ionizable amino lipid developed by BroadPharm to compare with SM-102. The propanolamine head improves encapsulation of mRNA. The lipid has two esters at C6 and C8 position relative to the amine nitrogen, ester linkages in the lipid tails are introduced into the structure to improve tissue clearance. The lipid has been evaluated by scientists and has shown greater transfection efficiency in two cell lines, HEK293Ts and Calu-3s- compared to SM-102 and other lipid analogs ( see product citation below).. Please contact us for GMP-grade inquiries.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > SM-102 & Analogs

Product Information

Catalog No.: BP-26399
CAS No.: 2244715-87-3
Molecular Formula: C45H89NO5
Molecular Weight: 724.2
Purity: 98%
Storage: -20°C
Solubility: Ethanol, DMSO, DMF
Availability: In Stock

Source

Original product source

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