t-Boc-N-amido-PEG2-CH2CO2-NHS ester is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
PEGylation of Protein, Peptide & Oligo > Amine Reactive > Boc-PEG | PEGylation of Protein, Peptide & Oligo > Amine Reactive > PEG NHS ester | Antibody Drug Conjugates > Amine Reactive > Boc-PEG | Antibody Drug Conjugates > Amine Reactive > PEG NHS ester | Drug Delivery, Surface Modification > Amine Reactive > Boc-PEG | Drug Delivery, Surface Modification > Amine Reactive > PEG NHS ester | Products > PEG Linkers > Boc-PEG | Products > PEG Linkers > Boc-PEG > t-Boc-N-amido-PEG-CH2CO2-NHS ester | Products > PEG Linkers > PEG NHS ester > t-Boc-N-amido-PEG-CH2CO2-NHS ester
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