Mal-amide-PEG8-Val-Cit-PAB-OH

Overview

Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.

Application

Products > PEG Linkers > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Val-Cit

Product Information

• Catalog No.: BP-40405
• CAS No.: 2387738-43-2
• Molecular Formula: C44H71N7O16
• Molecular Weight: 954.1
• Purity: 98%
• Storage: -20°C
• Solubility: Water, DMSO, DMF
• Availability: In Stock

Source

Original product source