BAMEA-O16B

CAS No.：2490668-30-7
Grade：95%
Formula：C56H111N3O6S6
M.W.：1114.9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

BAMEA-O16B is an ionizable lipid featuring disulfide bonds, designed for incorporation into lipid nanoparticles (LNPs) for efficient delivery of Cas9 mRNA and sgRNA. The disulfide linkages provide redox-sensitive degradability, enabling RNA release in the intracellular reductive environment. When formulated into LNPs, BAMEAO16B facilitates enhanced cellular uptake, endosomal escape, and intracellular bioavailability, supporting efficient genome editing. This lipid is ideally suited for gene editing research applications.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > 80-O18 & Analogs

Product Information

Catalog No.: BP-44592
CAS No.: 2490668-30-7
Molecular Formula: C56H111N3O6S6
Molecular Weight: 1114.9
Purity: 95%
Storage: -20°C
Availability: In Stock

Source

Original product source

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