MRT68921 (dihydrochloride) (Standard) is the analytical standard of MRT68921 (dihydrochloride) ( HY-100006A ). This product is intended for research and analytical applications. MRT68921 dihydrochloride is a potent NUAK1/ULK1 dual inhibitor. MRT68921 dihydrochloride inhibits ULK1 and ULK2 with IC50 values of 2.9 nM and 1.1 nM, respectively. MRT68921 dihydrochloride can block cells autophagy and kill tumor cells by breaking the balance of oxidative stress signals. MRT68921 dihydrochloride can inhibit cell proliferation and induce ROS production and apoptosis . MRT68921 dihydrochloride can be used for the research of cancer , such as breast cancer .
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