KDM5A-IN-1 (Standard)

Overview

KDM5A-IN-1 (Standard) is the analytical standard of KDM5A-IN-1 ( HY-100014 ). This product is intended for research and analytical applications. KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 ( KDM5 ) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B).

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Histone Demethylase | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-100014R
• CAS No.: 1905481-36-8
• Molecular Formula: C15H22N4O2
• Molecular Weight: 290.37
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source