MK-4101 (Standard)

Overview

MK-4101 (Standard) is the analytical standard of MK-4101 ( HY-100036 ). This product is intended for research and analytical applications. MK-4101 is a Smoothened ( SMO ) antagonist (IC50 of 1.1 μM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 μM for mouse cells; IC50 of 1 μM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis .

Application

Products | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Others | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Smo | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Hedgehog

Product Information

• Catalog No.: HY-100036R
• CAS No.: 935273-79-3
• Molecular Formula: C24H24F5N5O
• Molecular Weight: 493.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source