Varenicline Tartrate

Overview

Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR , IC 50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR . Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation.

Application

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Product Information

• Catalog No.: HY-10021
• CAS No.: 375815-87-5
• Molecular Formula: C17H19N3O6
• Molecular Weight: 361.35
• Purity: 99.96%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1.43 mg/mL (3.96 mM); Clear solution
• Availability: In-stock

Source

Original product source