IQ-1S (free acid) (Standard) is the analytical standard of IQ-1S (free acid) ( HY-100233 ). This product is intended for research and analytical applications. IQ-1S free acid is a prospective inhibitor of NF-κB/activating protein 1 ( AP-1 ) activity with an IC50 of 2.3±0.41 μM. IQ-1S free acid has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 100 nM, 240 nM, and 360 nM for JNK3 , JNK1 , and JNK2 , respectively.
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