RPR107393 free base

Overview

RPR107393 free base is an orally active potent selective squalene synthase ( SQS ) inhibitor. RPR107393 free base inhibits rat liver microsomal squalene synthase with an IC 50 value of 0.8 nM. RPR107393 free base reduces triglyceride biosynthesis by suppressing fatty acid biosynthesis via an increase in intracellular farnesol and its derivatives. RPR107393 free base reduces plasma cholesterol in rats and marmosets. RPR107393 free base can be used for metabolic disease research, such as hypercholesterolemia, hypertriglyceridemia and atherosclerosis [1][2] .

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Farnesyl Transferase

Product Information

• Catalog No.: HY-100299
• CAS No.: 197576-78-6
• Molecular Formula: C22H22N2O
• Molecular Weight: 330.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source