Quiflapon

Overview

Quiflapon (MK-591) is a selective and specific 5-lipoxygenase-activating protein ( FLAP ) inhibitor with an IC 50 of 1.6 nM in a FLAP binding assay. Quiflapon is also a potent and orally active Leukotriene biosynthesis (LT) inhibitor, shows IC 50 values of 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively. Quiflapon induces cell apoptosis .

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > FLAP | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-10037
• CAS No.: 136668-42-3
• Molecular Formula: C34H35ClN2O3S
• Molecular Weight: 587.17
• Purity: 99.44%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.5 mg/mL (4.26 mM); Suspended solution; Need ultrasonic and warming
• Availability: In-stock

Source

Original product source