Ticlopidine

CAS No.：55142-85-3
Grade：99.74%
Formula：C14H14ClNS
M.W.：263.79
Solvent：≥ 2.5 mg/mL (9.48 mM); Clear solution

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

Ticlopidine (PCR 5332), an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC 50 of 81.7 μM. Ticlopidine blocks several NTPDase isoenzymes with IC 50 s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively. Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine inhibits CYP2C9 and CYP3A4 with IC 50 s of 26.0 and 32.3 μM, respectively.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > NTPDase | Products > Signaling Pathways > Cytochrome P450

Product Information

Catalog No.: HY-100386
CAS No.: 55142-85-3
Molecular Formula: C14H14ClNS
Molecular Weight: 263.79
Purity: 99.74%
Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solubility: ≥ 2.5 mg/mL (9.48 mM); Clear solution
Availability: In-stock

Source

Original product source

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