Ro 67-7476 (Standard)

Overview

Ro 67-7476 (Standard) is the analytical standard of Ro 67-7476 ( HY-100403 ). This product is intended for research and analytical applications. Ro 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM).

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > mGluR | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-100403R
• CAS No.: 298690-60-5
• Molecular Formula: C17H18FNO2S
• Molecular Weight: 319.39
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source