Netoglitazone

Overview

Netoglitazone (MCC-555) is an orally active PPARγ ligand with an EC 50 of 8 μM. Netoglitazone mediates cell type-specific functional regulation, and modulates the transcriptional activity of PPARγ as a full agonist, partial agonist or antagonist. Netoglitazone induces adipogenesis, inhibits osteoblastogenesis, alters the weight of extramedullary fat depots and enhances insulin sensitivity. Netoglitazone reduces blood glucose levels. Netoglitazone can be used in research related to type 2 diabetes and non-insulin-dependent diabetes mellitus.

Application

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Product Information

• Catalog No.: HY-100428
• CAS No.: 161600-01-7
• Molecular Formula: C21H16FNO3S
• Molecular Weight: 381.42
• Purity: 99.92%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.45 mM); Clear solution
• Availability: In-stock

Source

Original product source