LOC14 (Standard)

Overview

LOC14 (Standard) is the analytical standard of LOC14 ( HY-100432 ). This product is intended for research and analytical applications. LOC14 is a potent Protein disulfide isomerase ( PDI ) inhibitor with EC50 and Kd values of 500 nM and 62 nM, respectively. LOC14 exhibits high stability in mouse liver microsomes and blood plasma, low intrinsic microsome clearance, and low plasma-protein binding. LOC14 inhibits PDIA3 activity, decreases intramolecular disulfide bonds and subsequent oligomerization (maturation) of HA in lung epithelial cells.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PDI | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-100432R
• CAS No.: 877963-94-5
• Molecular Formula: C16H19N3O2S
• Molecular Weight: 317.41
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source