PACMA 31 (Standard)

Overview

PACMA 31 (Standard) is the analytical standard of PACMA 31 ( HY-100433 ). This product is intended for research and analytical applications. PACMA 31 is an irreversible, orally active protein disulfide isomerase ( PDI ) inhibitor with an IC50 of 10 μM. PACMA 31 forms a covalent bond with the active site cysteines of PDI . PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues. PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PDI | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-100433R
• CAS No.: 1401089-31-3
• Molecular Formula: C21H22N2O6S
• Molecular Weight: 430.47
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source