TP-472 (Standard) is the analytical standard of TP-472 ( HY-100517 ). This product is intended for research and analytical applications. TP-472 , a chemical probe, is a selective BRD9/7 inhibitor, with Kds of 33 nM and 340 nM for BRD9 and BRD7, respectively. TP-472 exhibits >30-fold selectivity for BRD9 over other bromodomain family members except BRD7. TP-472 induces apoptosis of melanoma cells.
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