3-O-Methyltolcapone-d 7

Overview

3-O-Methyltolcapone-d 7 (Ro 40-7591 d 7 ) is a deuterium labeled 3-O-Methyltolcapone (HY-174062). 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone ( HY-17406 ). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC 50 of 773 nM. Tolcapone can inhibits α-syn and Aβ 42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease , such as Parkinson disease and neuroblastoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > COMT | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-100642S
• CAS No.: 2741390-22-5
• Molecular Formula: C15H6D7NO5
• Molecular Weight: 294.31
• Purity: 99.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source