Desmethyl cariprazine-d 8

Overview

Desmethyl cariprazine -d 8 is the deuterium labeled Desmethyl cariprazine ( HY-100656 ). Desmethyl cariprazine is a major active metabolite of cariprazine, with activities at human dopamine receptors and serotonin receptors, showing a pEC 50 of 8.90 at human D2 receptors, a pEC 50 of 8.09 at D3 receptors, and a pEC 50 of 6.28 at 5-HT1A receptors. Desmethyl cariprazine inhibits forskolin-induced cAMP production at D2, D3 and 5-HT1A receptors, and suppresses serotonin-induced Ca 2+ release at 5-HT2B receptors. Desmethyl cariprazine is applicable to research related to schizophrenia, bipolar disorder type I and bipolar disorder.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Dopamine Receptor

Product Information

• Catalog No.: HY-100656AS
• CAS No.: 1308278-85-4
• Molecular Formula: C20H22D8Cl2N4O
• Molecular Weight: 421.43
• Purity: 99.90%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source