ON1231320 (Standard)

Overview

ON1231320 (Standard) is the analytical standard of ON1231320 ( HY-100789 ). This product is intended for research and analytical applications. ON1231320 is a highly specific polo like kinase 2 ( PLK2 ) inhibitor with an IC50 of 0.31 μM. ON1231320 blocks tumor cell cycle progression in the G2/M phase in mitosis , causing apoptotic cell death. ON1231320 , an arylsulfonyl pyrido-pyrimidinone, has antitumor activity.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Others | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Mitosis | Products > Signaling Pathways > Polo-like Kinase (PLK) | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-100789R
• CAS No.: 1312471-39-8
• Molecular Formula: C22H15F2N5O3S
• Molecular Weight: 467.45
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source