SR12813 (Standard) is the analytical standard of SR12813 ( HY-100793 ). This product is intended for research and analytical applications. SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR).
Products | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Autophagy | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Pregnane X Receptor (PXR) | Products > Signaling Pathways > HMG-CoA Reductase (HMGCR) | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Autophagy
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