Quinolinic acid - 13 C 7 is the 13 C labeled Quinolinic acid ( HY-100807 ). Quinolinic acid , an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor ( NMDA receptor ) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS , activates nitric oxide synthase , produces excessive NO, leading to calcium ion influx and neuronal apoptosis .
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