NCB-0846 (Standard)

Overview

NCB-0846 (Standard) is the analytical standard of NCB-0846 ( HY-100830 ). This product is intended for research and analytical applications. NCB-0846 is an orally active, selective inhibitor for Wnt , that inhibits Traf2- and Nck-interacting kinase (TNIK) with an IC50 of 21 nM. NCB-0846 blocks TGF-β signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Wnt | Products > Signaling Pathways > MAP4K | Products > Signaling Pathways > TGF-beta/Smad

Product Information

• Catalog No.: HY-100830R
• CAS No.: 1792999-26-8
• Molecular Formula: C21H21N5O2
• Molecular Weight: 375.42
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source