5,7-Dichlorokynurenic acid (Standard)

5,7-Dichlorokynurenic acid (Standard)
  • CAS No.:131123-76-7
  • Grade:99.98%
  • Formula:C10H5Cl2NO3
  • M.W.:258.06

Overview

5,7-Dichlorokynurenic acid (Standard) is the analytical standard of 5,7-Dichlorokynurenic acid ( HY-100834 ). This product is intended for research and analytical applications. 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a K B of 65 nM. 5,7-Dichlorokynurenic acid reduces NMDA-induced neuron injury. 5,7-Dichlorokynurenic acid increases social interaction time, increases open arm exploration time, disinhibits suppressed conflict responding in rodent models. 5,7-Dichlorokynurenic acid exhibits anxiolytic-like activity in rodent models and supports exploration of glycine’s role in NMDA receptor-mediated synaptic transmission.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > iGluR

Product Information

  • Catalog No.: HY-100834R
  • CAS No.: 131123-76-7
  • Molecular Formula: C10H5Cl2NO3
  • Molecular Weight: 258.06
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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