Navitoclax

Navitoclax
  • CAS No.:923564-51-6
  • Grade:99.64%
  • Formula:C47H55ClF3N5O6S3
  • M.W.:974.61
  • Solvent:≥ 2.5 mg/mL (2.57 mM); Clear solution

Overview

Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-x L , Bcl-2 and Bcl-w , with a K i of less than 1 nM.

Application

Products | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > SARS-CoV-2 Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > Prostate Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcl-2 Family

Product Information

  • Catalog No.: HY-10087
  • CAS No.: 923564-51-6
  • Molecular Formula: C47H55ClF3N5O6S3
  • Molecular Weight: 974.61
  • Purity: 99.64%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 2.5 mg/mL (2.57 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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