ML364 (Standard)

Overview

ML364 (Standard) is the analytical standard of ML364 ( HY-100900 ). This product is intended for research and analytical applications. ML364 is a selective ubiquitin specific peptidase 2 ( USP2 ) inhibitor (IC50=1.1 μM) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 μM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Deubiquitinase | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-100900R
• CAS No.: 1991986-30-1
• Molecular Formula: C24H18F3N3O3S2
• Molecular Weight: 517.54
• Purity: 95%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source