ARV-771 (Standard)

Overview

ARV-771 (Standard) is the analytical standard of ARV-771 ( HY-100972 ). This product is intended for research and analytical applications. ARV-771 is a potent BET PROTAC based on E3 ligase von Hippel-Lindau with Kds of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively. (Pink: BET ligand ( HY-78695 ); Blue: VHL ligand ( HY-112078 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Others | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-100972R
• CAS No.: 1949837-12-0
• Molecular Formula: C49H60ClN9O7S2
• Molecular Weight: 986.64
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source