MBM-55 (Standard)

Overview

MBM-55 (Standard) is the analytical standard of MBM-55 ( HY-101029 ). This product is intended for research and analytical applications. MBM-55 is a potent NIMA-related kinase 2 ( Nek2 ) inhibitor with an IC50 of 1 nM. MBM-55 shows a 20-fold or greater selectivity in most kinases with the exception of RSK1 (IC50=5.4 nM) and DYRK1a (IC50=6.5 nM). MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis . MBM-55 shows antitumor activities, and no obvious toxicity to mice.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Others | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > NEKs | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-101029R
• CAS No.: 2083622-09-5
• Molecular Formula: C28H27FN6O2
• Molecular Weight: 498.55
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source