YKL-05-099 is a salt-inducible kinase ( SIK ) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC 50 s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC 50 =40 nM).
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Salt-inducible Kinase (SIK)
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