L-732138 (Standard)

Overview

L-732138 (Standard) is the analytical standard of L-732138 ( HY-101249 ). This product is intended for research and analytical applications. L-732138 is a selective, potent and competitive neurokinin-1 (NK-1) receptor antagonist with an IC50 of 2.3 nM. L-732138 has 200-fold more potent in cloned human NK-1 receptors than cloned rat NK-1 receptors, and has > 1000-fold more potent than human NK-2 and NK-3 receptors. L-732138 can reduce hyperalgesia and has antitumor action.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Neurokinin Receptor | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-101249R
• CAS No.: 148451-96-1
• Molecular Formula: C22H18F6N2O3
• Molecular Weight: 472.38
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source