SYM 2081 (Standard) is the analytical standard of SYM 2081 ( HY-101310 ). This product is intended for research and analytical applications. SYM 2081 is a kainate receptor agonist . SYM 2081 is a substrate of EAAT1 (Km of 54 μM). SYM 2081 inhibits EAAT2-mediated glutamate transport (Kb is 3.4 μM in Xenopus oocytes), modulates Apoptotic signaling pathways (increases Bcl-2 and decreases Bax/caspase-3 expression). SYM 2081 exhibits neuroprotective activity. SYM 2081 can be used in the study of hypoxic-ischemic brain damage and inflammatory or neuropathic pain.
Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > iGluR | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > EAAT | Products > Signaling Pathways > Bcl-2 Family
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