1-EBIO (1-Ethyl-2-benzimidazolinone) (Standard) is the analytical standard of 1-EBIO ( HY-101360 ). This product is intended for research and analytical applications. 1-EBIO is an activator of Ca 2+ sensitive K + channels wirh an EC 50 of 136 μM for K Ca 3.1. 1-EBIO induces Cl - secretion, K + conductance, membrane hyperpolarization, and afterhyperpolarisation currents. 1-EBIO reduces epileptiform activity, seizure incidence, and rescues cells from Ionomycin ( HY-13434 )-induced death.
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