Temuterkib (Standard)

Overview

Temuterkib (Standard) is the analytical standard of Temuterkib ( HY-101494 ). This product is intended for research and analytical applications. Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2 , with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations.

Application

Products | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Others | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > ERK | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-101494R
• CAS No.: 1951483-29-6
• Molecular Formula: C22H27N7O2S
• Molecular Weight: 453.56
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source