POLYBROMINATEDDIPHENYLETHER

CAS No.：80246-27-1

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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POLYBROMINATEDDIPHENYLETHER Basic information

Biological functions

Product Name:	POLYBROMINATEDDIPHENYLETHER
Synonyms:	POLYBROMINATEDDIPHENYLETHER;Phenol, 2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy)-
CAS:	80246-27-1
MF:	C12H4Br6O3
MW:	675.58
EINECS:
Product Categories:
Mol File:	80246-27-1.mol

POLYBROMINATEDDIPHENYLETHER Chemical Properties

Boiling point	454.5±45.0 °C(Predicted)
density	2.659±0.06 g/cm3(Predicted)
pka	4.67±0.50(Predicted)

Safety Information

MSDS Information

POLYBROMINATEDDIPHENYLETHER Usage And Synthesis

Biological functions	Reduced serum thyroxine levels and thyroid follicular cell hyperplasia were observed in rats and mice orally exposed to lower brominated PBDE mixtures.PBDE congeners BDE-19 and -10 inhibit AR binding.BDE-99 treatment during pregnancy reduced the estradiol-17β and testosterone levels in male offspring in rats,and affected the progesterone and estrogen receptor (ER)-α and -β levels in the uterus of female offspring.
Description	PBDEs are organobromine compounds used as flame retardants, and they show antiandrogenic and antithyroid activities.
Physical properties	Molecular formula C12H_{(10- x)}Br_xO. Soluble in acetone and benzene.

POLYBROMINATEDDIPHENYLETHER Preparation Products And Raw materials

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