Dabigatran -d 7 (BIBR 953-d 7 ; BIBR 953ZW-d 7 ) is the deuterium labeled Dabigatran ( HY-10163 ). Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC 50 =10 nM).
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Thrombin
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