Dasatinib (Standard)

Overview

Dasatinib (Standard) is the analytical standard of Dasatinib. This product is intended for research and analytical applications. Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl , respectively. Dasatinib inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively. Dasatinib also induces apoptosis and autophagy .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Bcr-Abl | Products > Signaling Pathways > Src | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-10181R
• CAS No.: 302962-49-8
• Molecular Formula: C22H26ClN7O2S
• Molecular Weight: 488.01
• Purity: 99.80%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source