TG 100801

Overview

TG 100801 is a proagent that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases ; has IC 50 s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1 , VEGFR2 , FGFR1 , FGFR2 , PDGFRβ , Fgr , Fyn , Hck , Lck , Lyn , Src , Yes , respectively.

Application

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Product Information

• Catalog No.: HY-10186
• CAS No.: 867331-82-6
• Molecular Formula: C33H30ClN5O3
• Molecular Weight: 580.08
• Purity: 98.61%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source