GSK-872 (Standard)

Overview

GSK-872 (Standard) is the analytical standard of GSK-872 ( HY-101872 ). This product is intended for research and analytical applications. GSK-872 is a RIPK3 inhibitor , which binds RIP3 kinase domain with an IC 50 of 1.8 nM, and inhibits kinase activity with an IC 50 of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > RIP kinase

Product Information

• Catalog No.: HY-101872R
• CAS No.: 1346546-69-7
• Molecular Formula: C19H17N3O2S2
• Molecular Weight: 383.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source