Autophinib (Standard) is the analytical standard of Autophinib ( HY-101920 ). This product is intended for research and analytical applications. Autophinib is a potent, selective autophagy inhibitor with IC 50 s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy , respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 ( VPS34 ) inhibitor with an IC 50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34 .
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