Everolimus- 13 C 2 ,d 4 (RAD001- 13 C 2 ,d 4 ) is 13 C labeled Everolimus. Everolimus (RAD001) is a Rapamycin ( HY-10219 ) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy . Everolimus has potent immunosuppressive and anticancer activities.
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