Panobinostat

Overview

Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells. Panobinostat induces cell apoptosis and autophagy . Panobinostat can be used for the study of refractory or relapsed multiple myeloma.

Application

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Product Information

• Catalog No.: HY-10224
• CAS No.: 404950-80-7
• Molecular Formula: C21H23N3O2
• Molecular Weight: 349.43
• Purity: 99.37%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 2.5 mg/mL (7.15 mM); Clear solution
• Availability: In-stock

Source

Original product source