THIP -d4 (Gaboxadol-d4) is the deuterium labeled THIP ( HY-10232 ). THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors ( eGABARs ) agonist (with blood-brain barrier permeability), shows an EC 50 value of 13 μM for δ-GABAAR . THIP induces strong tense GABAA -mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > GABA Receptor
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.