Simeprevir (Standard)

Overview

Simeprevir (Standard) is the analytical standard of Simeprevir ( HY-10241 ). This product is intended for research and analytical applications. Simeprevir (TMC435; TMC435350) is an oral, potent and highly specific hepatitis C virus ( HCV ) NS3/4A protease inhibitor with a K i of 0.36 nM. Simeprevir inhibits HCV replication with an EC 50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (Mpro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > HCV | Products > Signaling Pathways > HCV Protease | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-10241R
• CAS No.: 923604-59-5
• Molecular Formula: C38H47N5O7S2
• Molecular Weight: 749.94
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source