A-837093 sodium is a potent and orally active inhibitor of the hepatitis C virus ( HCV ) nonstructural protein 5B ( NS5B ) polymerase . A-837093 sodium shows potencies against polymerases derived from both HCV genotypes 1a ( IC 50 = 1.25 nM) and 1b ( IC 50 = 0.33 nM). A-837093 sodium exhibits antiviral efficacy in HCV-infected chimpanzees. A-837093 sodium can be used for HCV infection research.
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